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Q9D0I9

Arginine--tRNA ligase, cytoplasmic (Q9D0I9)

Uniprot ID Q9D0I9
Protein Name Arginine--tRNA ligase, cytoplasmic
Gene Name Rars
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.525
Function Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis (PubMed:12060739). Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1. .
GO - Molecular function
  • arginine binding : ISO:MGI
  • arginine-tRNA ligase activity : IMP:CAFA
  • ATP binding : ISO:MGI
  • cadherin binding : ISO:MGI
  • tRNA binding : ISO:MGI
GO - Biological process
  • arginyl-tRNA aminoacylation : IDA:CAFA
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.