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Q9CYK2

Glutaminyl-peptide cyclotransferase (Q9CYK2)

Uniprot ID Q9CYK2
Protein Name Glutaminyl-peptide cyclotransferase
Gene Name Qpct
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (3) Interactions
Signal peptide(a) Y Secretome P(b) 0.0
Function Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue (By similarity). .
GO - Molecular function
  • glutaminyl-peptide cyclotransferase activity : ISS:UniProtKB
  • zinc ion binding : ISS:UniProtKB
GO - Biological process
  • peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase : ISS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.