Coactosin-like protein (Q9CQI6)

Uniprot ID	Q9CQI6
Protein Name	Coactosin-like protein
Gene Name	Cotl1
Species	Mus musculus (Mouse)

Signal peptide^(a)	N	Secretome P^(b)	0.928
Function	Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis (By similarity). .
GO - Molecular function	actin binding : IDA:MGI enzyme binding : IPI:UniProtKB
GO - Biological process	defense response to fungus : IDA:UniProtKB

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}