Glia maturation factor beta (Q9CQI3)

Uniprot ID Q9CQI3
Protein Name Glia maturation factor beta
Gene Name Gmfb
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.786
Function This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. .
GO - Molecular function
  • actin binding : IEA:InterPro
  • Arp2/3 complex binding : IBA:GO_Central
  • growth factor activity : IEA:UniProtKB-KW
GO - Biological process
  • actin filament debranching : IBA:GO_Central
  • learning : IMP:MGI
  • locomotory behavior : IMP:MGI
  • negative regulation of Arp2/3 complex-mediated actin nucleation : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.