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Q99KI0

Aconitate hydratase, mitochondrial (Q99KI0)

Uniprot ID Q99KI0
Protein Name Aconitate hydratase, mitochondrial
Gene Name Aco2
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (5) Interactions
Signal peptide(a) N Secretome P(b) 0.438
Function Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. .
GO - Molecular function
  • 3 iron, 4 sulfur cluster binding : ISO:MGI
  • 4 iron, 4 sulfur cluster binding : ISO:MGI
  • aconitate hydratase activity : IDA:MGI
  • iron ion binding : ISO:MGI
GO - Biological process
  • citrate metabolic process : ISO:MGI
  • isocitrate metabolic process : ISO:MGI
  • liver development : IEA:Ensembl
  • response to isolation stress : IEA:Ensembl
  • tricarboxylic acid cycle : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.