Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
Q922D8

C-1-tetrahydrofolate synthase, cytoplasmic (Q922D8)

Uniprot ID Q922D8
Protein Name C-1-tetrahydrofolate synthase, cytoplasmic
Gene Name Mthfd1
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.507
Function
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • formate-tetrahydrofolate ligase activity : IMP:BHF-UCL
  • methenyltetrahydrofolate cyclohydrolase activity : IBA:GO_Central
  • methylenetetrahydrofolate dehydrogenase (NAD+) activity : IDA:BHF-UCL
  • methylenetetrahydrofolate dehydrogenase (NADP+) activity : IBA:GO_Central
GO - Biological process
  • 10-formyltetrahydrofolate biosynthetic process : IMP:BHF-UCL
  • heart development : IMP:BHF-UCL
  • histidine biosynthetic process : IEA:UniProtKB-KW
  • methionine biosynthetic process : ISO:MGI
  • methionine metabolic process : IMP:BHF-UCL
  • neural tube closure : IMP:BHF-UCL
  • neutrophil homeostasis : IMP:BHF-UCL
  • one-carbon metabolic process : ISO:MGI
  • purine nucleobase biosynthetic process : IBA:GO_Central
  • purine nucleotide biosynthetic process : IMP:BHF-UCL
  • serine family amino acid biosynthetic process : ISO:MGI
  • serine family amino acid metabolic process : IMP:BHF-UCL
  • somite development : IMP:BHF-UCL
  • tetrahydrofolate interconversion : IMP:BHF-UCL
  • transsulfuration : IMP:BHF-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.