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Q8QZR5

Alanine aminotransferase 1 (Q8QZR5)

Uniprot ID Q8QZR5
Protein Name Alanine aminotransferase 1
Gene Name Gpt
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (7) Interactions
Signal peptide(a) N Secretome P(b) 0.574
Function Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity). .
GO - Molecular function
  • L-alanine : ISO:MGI
  • pyridoxal phosphate binding : IEA:InterPro
GO - Biological process
  • biosynthetic process : IEA:InterPro
  • L-alanine catabolic process : IEA:UniProtKB-UniPathway
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.