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Q8K2B3

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (Q8K2B3 )

Uniprot ID Q8K2B3
Protein Name Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Gene Name Sdha
Species Mus musculus (Mouse)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. .
GO - Molecular function
  • electron transfer activity : IBA:GO_Central
  • flavin adenine dinucleotide binding : IEA:InterPro
  • succinate dehydrogenase (ubiquinone) activity : ISS:UniProtKB
GO - Biological process
  • anaerobic respiration : IBA:GO_Central
  • mitochondrial electron transport, succinate to ubiquinone : IBA:GO_Central
  • nervous system development : ISO:MGI
  • oxidation-reduction process : ISO:MGI
  • respiratory electron transport chain : ISS:UniProtKB
  • succinate metabolic process : ISS:UniProtKB
  • tricarboxylic acid cycle : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.