Pyridoxal kinase (Q8K183)

Uniprot ID Q8K183
Protein Name Pyridoxal kinase
Gene Name Pdxk
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.858
Function Required for synthesis of pyridoxal-5-phosphate from vitamin B6. .
GO - Molecular function
  • ATP binding : ISO:MGI
  • drug binding : ISO:MGI
  • lithium ion binding : ISO:MGI
  • magnesium ion binding : ISO:MGI
  • potassium ion binding : ISO:MGI
  • protein homodimerization activity : ISO:MGI
  • pyridoxal binding : ISO:MGI
  • pyridoxal kinase activity : ISO:MGI
  • pyridoxal phosphate binding : ISO:MGI
  • sodium ion binding : ISO:MGI
  • zinc ion binding : ISO:MGI
GO - Biological process
  • cell proliferation : ISO:MGI
  • negative regulation of apoptotic process : ISO:MGI
  • pyridoxal 5'-phosphate salvage : IBA:GO_Central
  • pyridoxal phosphate biosynthetic process : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.