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Q6WVG3

BTB/POZ domain-containing protein KCTD12 (Q6WVG3)

Uniprot ID Q6WVG3
Protein Name BTB/POZ domain-containing protein KCTD12
Gene Name Kctd12
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.0
Function Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization. .
GO - Molecular function
  • identical protein binding : ISO:MGI
GO - Biological process
  • protein homooligomerization : IEA:InterPro
  • regulation of G-protein coupled receptor protein signaling pathway : IGI:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.