| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). . |
| GO - Molecular function |
- amino acid binding : IDA:RGD
- carboxylic acid binding : IDA:RGD
- enzyme binding : IDA:RGD
- identical protein binding : IMP:RGD
- kynurenine-oxoglutarate transaminase activity : IEA:UniProtKB-EC
- L-aspartate : IDA:RGD
- phospholipid binding : IDA:RGD
- pyridoxal phosphate binding : IDA:RGD
|
| GO - Biological process |
- 2-oxoglutarate metabolic process : ISS:UniProtKB
- aspartate biosynthetic process : ISO:RGD
- aspartate catabolic process : ISO:RGD
- aspartate metabolic process : IMP:RGD
- cellular amino acid metabolic process : IDA:RGD
- dicarboxylic acid metabolic process : IDA:RGD
- fatty acid transport : ISO:RGD
- female pregnancy : IEP:RGD
- glutamate catabolic process to 2-oxoglutarate : IDA:RGD
- glutamate catabolic process to aspartate : ISO:RGD
- glutamate metabolic process : ISS:UniProtKB
- lactation : IEP:RGD
- oxaloacetate metabolic process : IDA:RGD
- response to ethanol : ISO:RGD
- response to insulin : IEP:RGD
- response to morphine : IEP:RGD
- response to muscle activity : IEP:RGD
|