Rab GDP dissociation inhibitor beta (Q61598)

Uniprot ID Q61598
Protein Name Rab GDP dissociation inhibitor beta
Gene Name Gdi2
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.435
Function Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
GO - Molecular function
  • GTPase activator activity : IPI:MGI
  • Rab GDP-dissociation inhibitor activity : ISO:MGI
  • small GTPase binding : ISO:MGI
GO - Biological process
  • protein transport : IEA:InterPro
  • small GTPase mediated signal transduction : IPI:MGI
  • vesicle-mediated transport : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.