FK506-binding protein 15 (Q5T1M5)

Uniprot ID Q5T1M5
Protein Name FK506-binding protein 15
Gene Name FKBP15
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b)
Function May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase (By similarity). Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement. .
GO - Molecular function
  • actin binding : IEA:UniProtKB-KW
  • peptidyl-prolyl cis-trans isomerase activity : IEA:InterPro
GO - Biological process
  • endocytosis : IEA:UniProtKB-KW
  • negative regulation of phosphatase activity : IDA:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.