Clustered mitochondria protein homolog (Q5SW19)

Uniprot ID Q5SW19
Protein Name Clustered mitochondria protein homolog
Gene Name Cluh
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.0
Function mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis. .
GO - Molecular function
  • mRNA binding : ISS:UniProtKB
GO - Biological process
  • intracellular distribution of mitochondria : ISS:UniProtKB
  • mitochondrion organization : ISS:UniProtKB
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.