Uniprot ID | Q5FVH2 | ||
Protein Name | 5'-3' exonuclease PLD3 | ||
Gene Name | Pld3 | ||
Species | Rattus norvegicus (Rat) |
Signal peptide(a) | N | Secretome P(b) | |
Function | 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (By similarity). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity). May be important in myotube formation. Plays a role in lysosomal homeostasis. Involved in the regulation of endosomal protein sorting (By similarity). . | ||
GO - Molecular function |
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GO - Biological process |
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