Signal peptide(a) |
N |
Secretome P(b) |
0.694 |
Function |
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane. . |
GO - Molecular function |
- mannose binding : ISS:UniProtKB
|
GO - Biological process |
- brain development : ISS:UniProtKB
- glycosylation : ISS:UniProtKB
- lysosomal lumen acidification : ISS:UniProtKB
- lysosome organization : IMP:MGI
- neurogenesis : ISS:UniProtKB
- positive regulation of GTP binding : ISO:MGI
- retrograde transport, endosome to Golgi : ISO:MGI
- signal peptide processing : ISS:UniProtKB
- visual perception : IMP:MGI
|