Creatine kinase B-type (Q04447)

Uniprot ID Q04447
Protein Name Creatine kinase B-type
Gene Name Ckb
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.404
Function Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • creatine kinase activity : IEA:UniProtKB-EC
  • ubiquitin protein ligase binding : ISO:MGI
GO - Biological process
  • cellular chloride ion homeostasis : ISO:MGI
  • cerebellum development : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.