Protein transport protein Sec23A (Q01405)

Uniprot ID Q01405
Protein Name Protein transport protein Sec23A
Gene Name Sec23a
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.711
Function Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. .
GO - Molecular function
  • zinc ion binding : ISS:UniProtKB
GO - Biological process
  • cargo loading into COPII-coated vesicle : ISS:UniProtKB
  • intracellular protein transport : TAS:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.