Signal peptide(a) |
Y |
Secretome P(b) |
0.483 |
Function |
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). . |
GO - Molecular function |
- apolipoprotein binding : IDA:BHF-UCL
- calcium ion binding : IEA:InterPro
- calcium-dependent protein binding : IPI:BHF-UCL
- cargo receptor activity : IDA:BHF-UCL
- low-density lipoprotein particle receptor activity : TAS:ProtInc
- reelin receptor activity : ISS:BHF-UCL
- very-low-density lipoprotein particle binding : IDA:BHF-UCL
- very-low-density lipoprotein particle receptor activity : IDA:BHF-UCL
|
GO - Biological process |
- axon guidance : TAS:Reactome
- cholesterol metabolic process : IEA:UniProtKB-KW
- dendrite morphogenesis : IEA:Ensembl
- glycoprotein transport : IDA:BHF-UCL
- lipid transport : IEA:UniProtKB-KW
- low-density lipoprotein particle receptor catabolic process : TAS:Reactome
- memory : TAS:ProtInc
- nervous system development : TAS:ProtInc
- positive regulation of dendrite development : ISS:BHF-UCL
- positive regulation of protein kinase activity : IEA:Ensembl
- receptor-mediated endocytosis : IDA:BHF-UCL
- reelin-mediated signaling pathway : ISS:BHF-UCL
- signal transduction : TAS:ProtInc
- ventral spinal cord development : IEA:Ensembl
- very-low-density lipoprotein particle clearance : IDA:BHF-UCL
|