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P97885

C-X-C motif chemokine 5 (P97885)

Uniprot ID P97885
Protein Name C-X-C motif chemokine 5
Gene Name Cxcl5
Species Rattus norvegicus (Rat)
Basic Information Experiments (4) Disease (2) Interactions
Signal peptide(a) Y Secretome P(b)
Function May participate in the recruitment of inflammatory cells by injured or infected tissue. .
GO - Molecular function
  • chemokine activity : IMP:RGD
  • CXCR chemokine receptor binding : IBA:GO_Central
GO - Biological process
  • animal organ regeneration : IMP:RGD
  • antimicrobial humoral immune response mediated by antimicrobial peptide : ISO:RGD
  • cellular response to lipopolysaccharide : IEP:RGD
  • chemokine-mediated signaling pathway : IBA:GO_Central
  • cytokine production : IMP:RGD
  • immune response : IBA:GO_Central
  • inflammatory response : IMP:RGD
  • leukocyte chemotaxis : IBA:GO_Central
  • leukocyte homeostasis : ISO:RGD
  • midbrain development : IEP:RGD
  • neutrophil activation : ISO:RGD
  • neutrophil chemotaxis : ISO:RGD
  • positive regulation of neuron projection development : IMP:RGD
  • positive regulation of receptor signaling pathway via JAK-STAT : IDA:RGD
  • regulation of chemokine production : ISO:RGD
  • regulation of neutrophil mediated killing of gram-negative bacterium : ISO:RGD
  • response to gamma radiation : IEP:RGD
  • response to lipopolysaccharide : ISO:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.