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P97620

Lysosome-associated membrane glycoprotein 1 (P97620)

Uniprot ID P97620
Protein Name Lysosome-associated membrane glycoprotein 1
Gene Name Lamp1
Species Rattus norvegicus (Rat)
Basic Information Experiments (2) Disease (3) Interactions
Signal peptide(a) Y Secretome P(b)
Function Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
GO - Molecular function
  • enzyme binding : ISO:RGD
  • protein domain specific binding : ISO:RGD
GO - Biological process
  • autophagic cell death : IDA:RGD
  • establishment of protein localization to organelle : ISO:RGD
  • Golgi to lysosome transport : ISO:RGD
  • granzyme-mediated apoptotic signaling pathway : ISO:RGD
  • positive regulation of natural killer cell degranulation : ISO:RGD
  • positive regulation of natural killer cell mediated cytotoxicity : ISO:RGD
  • protein stabilization : ISS:UniProtKB
  • regulation of organelle transport along microtubule : ISO:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.