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P80313

T-complex protein 1 subunit eta (P80313)

Uniprot ID P80313
Protein Name T-complex protein 1 subunit eta
Gene Name Cct7
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.55
Function Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • identical protein binding : IPI:MGI
  • protein binding involved in protein folding : IBA:GO_Central
  • unfolded protein binding : IBA:GO_Central
GO - Biological process
  • 'de novo' protein folding : IBA:GO_Central
  • binding of sperm to zona pellucida : IDA:MGI
  • chaperone-mediated protein folding : IBA:GO_Central
  • positive regulation of establishment of protein localization to telomere : ISO:MGI
  • positive regulation of telomere maintenance via telomerase : ISO:MGI
  • protein stabilization : ISO:MGI
  • toxin transport : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.