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P70670

Nascent polypeptide-associated complex subunit alpha, muscle-specific form (P70670)

Uniprot ID P70670
Protein Name Nascent polypeptide-associated complex subunit alpha, muscle-specific form
Gene Name Naca
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (2) Interactions
Signal peptide(a) N Secretome P(b) 0.357
Function Cardiac-and muscle-specific transcription factor. May act to regulate the expression of genes involved in the development of myotubes. Plays a critical role in ventricular cardiomyocyte expansion and regulates postnatal skeletal muscle growth and regeneration. Involved in the organized assembly of thick and thin filaments of myofibril sarcomeres. .
GO - Molecular function
  • DNA binding : IEA:UniProtKB-KW
  • TBP-class protein binding : IDA:MGI
  • transcription coactivator activity : IDA:MGI
GO - Biological process
  • myoblast migration : IMP:MGI
  • regulation of transcription, DNA-templated : IEA:UniProtKB-KW
  • transcription, DNA-templated : IEA:UniProtKB-KW
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.