Signal peptide(a) |
N |
Secretome P(b) |
|
Function |
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity). Binds single-stranded DNA with higher affinity than double-stranded DNA. May play an important role in the metabolism of antibiotics. . |
GO - Molecular function |
- cysteine-type endopeptidase activity : IEA:InterPro
- cysteine-type peptidase activity : IBA:GO_Central
- identical protein binding : ISO:RGD
- peptidase activity : ISO:RGD
|
GO - Biological process |
- homocysteine catabolic process : IBA:GO_Central
- response to drug : ISO:RGD
- response to toxic substance : ISO:RGD
|