Signal peptide(a) |
N |
Secretome P(b) |
0.455 |
Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity). . |
GO - Molecular function |
- actin binding : IDA:ProtInc
- enzyme binding : ISO:MGI
- glucocorticoid receptor binding : ISS:UniProtKB
- identical protein binding : ISO:MGI
- ion channel binding : IPI:BHF-UCL
- protein domain specific binding : IDA:MGI
- protein heterodimerization activity : ISO:MGI
- sodium channel regulator activity : ISS:BHF-UCL
|
GO - Biological process |
- cytoskeleton organization : NAS:ProtInc
- glucocorticoid catabolic process : ISS:UniProtKB
- glucocorticoid receptor signaling pathway : ISS:UniProtKB
- intracellular protein transport : IDA:MGI
- membrane depolarization during action potential : ISS:BHF-UCL
- negative regulation of apoptotic process : NAS:ProtInc
- negative regulation of dendrite morphogenesis : IDA:MGI
- positive regulation of transcription, DNA-templated : ISS:UniProtKB
- regulation of mitotic nuclear division : NAS:ProtInc
- regulation of sodium ion transmembrane transporter activity : ISS:BHF-UCL
- regulation of sodium ion transport : ISS:BHF-UCL
|