| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity). . |
| GO - Molecular function |
- 14-3-3 protein binding : IPI:RGD
- identical protein binding : ISO:RGD
- ion channel binding : IPI:RGD
- protein C-terminus binding : IPI:RGD
- protein domain specific binding : ISO:RGD
- protein N-terminus binding : IPI:RGD
|
| GO - Biological process |
- negative regulation of ion transmembrane transport : IMP:RGD
- negative regulation of transcription, DNA-templated : ISO:RGD
- protein targeting : ISO:RGD
- small GTPase mediated signal transduction : ISO:RGD
|