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P63260

Actin, cytoplasmic 2 (P63260)

Uniprot ID P63260
Protein Name Actin, cytoplasmic 2
Gene Name Actg1
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.691
Function Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • identical protein binding : ISO:MGI
  • profilin binding : ISO:MGI
  • structural constituent of cytoskeleton : IDA:MGI
  • ubiquitin protein ligase binding : ISO:MGI
GO - Biological process
  • cellular response to interferon-gamma : IDA:MGI
  • response to calcium ion : IEA:Ensembl
  • response to mechanical stimulus : IEA:Ensembl
  • sarcomere organization : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.