Translationally-controlled tumor protein (P63028)

Uniprot ID P63028
Protein Name Translationally-controlled tumor protein
Gene Name Tpt1
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.802
Function Involved in calcium binding and microtubule stabilization. .
GO - Molecular function
  • calcium ion binding : ISO:MGI
  • microtubule binding : IBA:GO_Central
  • transcription factor binding : IPI:BHF-UCL
GO - Biological process
  • cell differentiation : IBA:GO_Central
  • negative regulation of ectoderm development : IMP:BHF-UCL
  • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage : ISO:MGI
  • spermatogenesis : IEA:Ensembl
  • stem cell population maintenance : IMP:BHF-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.