Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (P62715)

Uniprot ID P62715
Protein Name Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Gene Name Ppp2cb
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.644
Function PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
GO - Molecular function
  • metal ion binding : IEA:UniProtKB-KW
  • phosphoprotein phosphatase activity : ISO:MGI
  • protein C-terminus binding : ISO:MGI
  • protein serine/threonine phosphatase activity : ISO:MGI
GO - Biological process
  • apoptotic mitochondrial changes : IMP:MGI
  • negative regulation of Ras protein signal transduction : ISO:MGI
  • positive regulation of microtubule binding : ISO:MGI
  • proteasome-mediated ubiquitin-dependent protein catabolic process : IMP:MGI
  • protein dephosphorylation : ISO:MGI
  • regulation of gene expression : IMP:MGI
  • response to antibiotic : IMP:MGI
  • response to endoplasmic reticulum stress : IMP:MGI
  • response to hydrogen peroxide : IMP:MGI
  • response to lead ion : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.