| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G-and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. . |
| GO - Molecular function |
- ATP binding : IEA:UniProtKB-KW
- identical protein binding : ISO:RGD
- kinesin binding : ISO:RGD
- nitric-oxide synthase binding : ISO:RGD
- protein kinase binding : IPI:RGD
- structural constituent of postsynaptic actin cytoskeleton : ISO:RGD
- Tat protein binding : ISO:RGD
|
| GO - Biological process |
- axonogenesis : IDA:RGD
- cell motility : ISO:RGD
- cellular response to cytochalasin B : ISO:RGD
- cellular response to electrical stimulus : IDA:RGD
- circadian rhythm : IEP:RGD
- negative regulation of protein binding : ISO:RGD
- postsynaptic actin cytoskeleton organization : ISO:RGD
- regulation of cyclin-dependent protein serine/threonine kinase activity : IMP:ARUK-UCL
- regulation of norepinephrine uptake : IMP:ARUK-UCL
- regulation of protein localization to plasma membrane : ISO:RGD
- regulation of transmembrane transporter activity : IMP:ARUK-UCL
- response to immobilization stress : IEP:RGD
- response to mechanical stimulus : IEP:RGD
- retina development in camera-type eye : IEP:RGD
- synaptic vesicle endocytosis : ISO:RGD
|