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P60710

Actin, cytoplasmic 1 (P60710)

Uniprot ID P60710
Protein Name Actin, cytoplasmic 1
Gene Name Actb
Species Mus musculus (Mouse)
Basic Information Experiments (4) Disease (10) Interactions
Signal peptide(a) N Secretome P(b) 0.69
Function Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • identical protein binding : ISO:MGI
  • kinesin binding : ISO:MGI
  • nitric-oxide synthase binding : ISO:MGI
  • protein kinase binding : ISO:MGI
  • structural constituent of postsynaptic actin cytoskeleton : ISO:MGI
  • Tat protein binding : ISO:MGI
GO - Biological process
  • axonogenesis : ISO:MGI
  • cell motility : ISO:MGI
  • cellular response to cytochalasin B : ISO:MGI
  • cellular response to electrical stimulus : ISO:MGI
  • negative regulation of cyclin-dependent protein kinase activity : IC:ARUK-UCL
  • negative regulation of protein binding : IDA:ARUK-UCL
  • postsynaptic actin cytoskeleton organization : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.