| Signal peptide(a) |
N |
Secretome P(b) |
0.461 |
| Function |
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. |
| GO - Molecular function |
- 5S rRNA binding : ISO:MGI
- actin filament binding : ISO:MGI
- cadherin binding : ISO:MGI
- GTP binding : IEA:UniProtKB-KW
- GTPase activity : IDA:MGI
- p53 binding : ISO:MGI
- protein kinase binding : ISO:MGI
- ribosome binding : ISO:MGI
- RNA binding : ISO:MGI
- translation elongation factor activity : IEA:UniProtKB-KW
|
| GO - Biological process |
- aging : IEA:Ensembl
- cellular response to brain-derived neurotrophic factor stimulus : IEA:Ensembl
- glial cell proliferation : IEA:Ensembl
- hematopoietic progenitor cell differentiation : IMP:MGI
- positive regulation of cytoplasmic translation : ISO:MGI
- positive regulation of translation : ISO:MGI
- response to endoplasmic reticulum stress : IEA:Ensembl
- response to estradiol : IEA:Ensembl
- response to ethanol : IEA:Ensembl
- response to folic acid : IEA:Ensembl
- response to hydrogen peroxide : IEA:Ensembl
- response to ischemia : IEA:Ensembl
- skeletal muscle cell differentiation : IEA:Ensembl
- skeletal muscle contraction : IEA:Ensembl
- translational elongation : IDA:MGI
|