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P57776

Elongation factor 1-delta (P57776)

Uniprot ID P57776
Protein Name Elongation factor 1-delta
Gene Name Eef1d
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.0
Function [Isoform 1]: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. .[Isoform 3]: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE). {ECO:0000250|UniProtKB:P29692}.
GO - Molecular function
  • activating transcription factor binding : ISO:MGI
  • DNA binding : ISO:MGI
  • guanyl-nucleotide exchange factor activity : IBA:GO_Central
  • heat shock protein binding : ISO:MGI
  • translation elongation factor activity : IEA:UniProtKB-KW
GO - Biological process
  • cellular response to ionizing radiation : ISO:MGI
  • mRNA transcription : ISO:MGI
  • regulation of cell death : ISO:MGI
  • translational elongation : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.