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P50247

Adenosylhomocysteinase (P50247)

Uniprot ID P50247
Protein Name Adenosylhomocysteinase
Gene Name Ahcy
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.668
Function Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
GO - Molecular function
  • adenosylhomocysteinase activity : IDA:MGI
  • adenyl nucleotide binding : ISO:MGI
  • copper ion binding : IDA:MGI
  • identical protein binding : ISO:MGI
  • NAD binding : ISO:MGI
  • protein self-association : IPI:MGI
GO - Biological process
  • chronic inflammatory response to antigenic stimulus : ISO:MGI
  • circadian sleep/wake cycle : ISO:MGI
  • homocysteine biosynthetic process : ISO:MGI
  • one-carbon metabolic process : IEA:UniProtKB-KW
  • response to nutrient : ISO:MGI
  • S-adenosylhomocysteine catabolic process : IDA:MGI
  • S-adenosylmethionine cycle : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.