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P48036

Annexin A5 (P48036)

Uniprot ID P48036
Protein Name Annexin A5
Gene Name Anxa5
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.633
Function This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • calcium-dependent phospholipid binding : ISO:MGI
  • calcium-transporting ATPase activity : ISO:MGI
  • peptide hormone binding : ISO:MGI
  • receptor tyrosine kinase binding : ISO:MGI
GO - Biological process
  • blood coagulation : IEA:UniProtKB-KW
  • cellular response to gonadotropin-releasing hormone : ISO:MGI
  • negative regulation of blood coagulation : ISO:MGI
  • negative regulation of prolactin secretion : ISO:MGI
  • positive regulation of apoptotic process : ISO:MGI
  • protein homooligomerization : ISO:MGI
  • regulation of flagellated sperm motility : ISO:MGI
  • response to calcium ion : ISO:MGI
  • response to organic substance : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.