F-actin-capping protein subunit alpha-2 (P47754)

Uniprot ID	P47754
Protein Name	F-actin-capping protein subunit alpha-2
Gene Name	Capza2
Species	Mus musculus (Mouse)

Signal peptide^(a)	N	Secretome P^(b)	0.667
Function	F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
GO - Molecular function	actin binding : IEA:UniProtKB-KW
GO - Biological process	barbed-end actin filament capping : IEA:InterPro

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}