| Signal peptide(a) |
Y |
Secretome P(b) |
|
| Function |
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Plays a role in regulating insulin secretion in response to GLP-1 (By similarity). . |
| GO - Molecular function |
- G protein-coupled peptide receptor activity : IBA:GO_Central
- glucagon receptor activity : IEA:InterPro
- glucagon-like peptide 1 receptor activity : IDA:UniProtKB
- peptide hormone binding : IBA:GO_Central
- transmembrane signaling receptor activity : TAS:ProtInc
|
| GO - Biological process |
- activation of adenylate cyclase activity : TAS:ProtInc
- adenylate cyclase-activating G protein-coupled receptor signaling pathway : IDA:UniProtKB
- cAMP-mediated signaling : IDA:UniProtKB
- cell surface receptor signaling pathway : IEA:InterPro
- G protein-coupled receptor signaling pathway : TAS:Reactome
- learning or memory : IEA:Ensembl
- positive regulation of blood pressure : IBA:GO_Central
- positive regulation of cytosolic calcium ion concentration : IDA:UniProtKB
- regulation of heart contraction : IEA:Ensembl
- regulation of insulin secretion : TAS:Reactome
- response to psychosocial stress : IEA:Ensembl
|