| Signal peptide(a) |
Y |
Secretome P(b) |
0.574 |
| Function |
Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). . |
| GO - Molecular function |
- endopeptidase activity : ISO:MGI
- fibronectin binding : ISO:MGI
- identical protein binding : ISO:MGI
- metalloendopeptidase activity : IDA:MGI
- metallopeptidase activity : IDA:CAFA
- peptidase activity : IDA:MGI
- protein-containing complex binding : ISO:MGI
- serine-type endopeptidase activity : ISO:MGI
- zinc ion binding : IEA:InterPro
|
| GO - Biological process |
- aging : ISO:MGI
- cellular response to cadmium ion : ISO:MGI
- cellular response to cell-matrix adhesion : ISO:MGI
- cellular response to reactive oxygen species : ISO:MGI
- collagen catabolic process : IDA:MGI
- embryo implantation : IDA:MGI
- endodermal cell differentiation : IEA:Ensembl
- extracellular matrix organization : IMP:MGI
- heart development : ISO:MGI
- leukocyte migration : IEA:InterPro
- negative regulation of apoptotic process : ISO:MGI
- negative regulation of cation channel activity : ISO:MGI
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway : ISO:MGI
- negative regulation of fibroblast proliferation : ISO:MGI
- negative regulation of intrinsic apoptotic signaling pathway : ISO:MGI
- ossification : IEA:InterPro
- positive regulation of angiogenesis : ISO:MGI
- positive regulation of apoptotic process : IMP:MGI
- positive regulation of DNA binding : ISO:MGI
- positive regulation of epidermal growth factor receptor signaling pathway : ISO:MGI
- positive regulation of keratinocyte migration : ISO:MGI
- positive regulation of leukocyte migration : ISO:MGI
- positive regulation of protein phosphorylation : ISO:MGI
- positive regulation of receptor binding : ISO:MGI
- positive regulation of release of cytochrome c from mitochondria : ISO:MGI
- positive regulation of synaptic plasticity : ISO:MGI
- positive regulation of vascular smooth muscle cell proliferation : ISO:MGI
- protein complex oligomerization : ISO:MGI
- proteolysis : ISS:UniProtKB
- response to drug : ISO:MGI
- response to oxidative stress : ISO:MGI
- skeletal system development : IMP:MGI
- tissue remodeling : ISO:MGI
- transformation of host cell by virus : ISO:MGI
|