Ras-related protein Rab-6A (P35279)

Uniprot ID P35279
Protein Name Ras-related protein Rab-6A
Gene Name Rab6a
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b)
Function Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER (By similarity). .
GO - Molecular function
  • ATPase activator activity : ISO:MGI
  • ATPase binding : ISO:MGI
  • GTP binding : ISS:UniProtKB
  • GTPase activity : ISS:UniProtKB
  • myosin V binding : ISO:MGI
  • protein domain specific binding : ISO:MGI
GO - Biological process
  • antigen processing and presentation : ISO:MGI
  • early endosome to Golgi transport : ISO:MGI
  • intra-Golgi vesicle-mediated transport : IBA:GO_Central
  • intracellular protein transport : TAS:MGI
  • peptidyl-cysteine methylation : ISO:MGI
  • protein localization to Golgi apparatus : ISS:UniProtKB
  • retrograde transport, endosome to Golgi : IBA:GO_Central
  • retrograde vesicle-mediated transport, Golgi to ER : ISS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.