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P27773

Protein disulfide-isomerase A3 (P27773)

Uniprot ID P27773
Protein Name Protein disulfide-isomerase A3
Gene Name Pdia3
Species Mus musculus (Mouse)
Basic Information Experiments (4) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.42
Function
GO - Molecular function
  • identical protein binding : ISO:MGI
  • MHC class I protein binding : ISO:MGI
  • peptidase activity : ISO:MGI
  • peptide disulfide oxidoreductase activity : ISO:MGI
  • protein disulfide isomerase activity : IBA:GO_Central
  • protein-disulfide reductase (glutathione) activity : ISO:MGI
GO - Biological process
  • cell redox homeostasis : IEA:InterPro
  • cellular response to vitamin D : ISO:MGI
  • positive regulation of extrinsic apoptotic signaling pathway : IMP:MGI
  • positive regulation of protein folding : ISO:MGI
  • protein folding : IBA:GO_Central
  • response to endoplasmic reticulum stress : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.