Signal peptide(a) |
N |
Secretome P(b) |
0.32 |
Function |
Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. |
GO - Molecular function |
- actin filament binding : IEA:InterPro
- cadherin binding : ISO:MGI
- integrin binding : IMP:CAFA
- LIM domain binding : ISO:MGI
- phosphatidylinositol binding : IMP:CAFA
- phosphatidylserine binding : IMP:CAFA
- protein-containing complex binding : ISO:MGI
- structural constituent of cytoskeleton : IEA:InterPro
- vinculin binding : ISO:MGI
|
GO - Biological process |
- cell adhesion : IEA:InterPro
- cell-substrate junction assembly : IMP:MGI
- cortical actin cytoskeleton organization : IMP:MGI
- cytoskeletal anchoring at plasma membrane : IEA:InterPro
- integrin activation : IMP:CAFA
- integrin-mediated signaling pathway : IMP:CAFA
|