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P25113

Phosphoglycerate mutase 1 (P25113)

Uniprot ID P25113
Protein Name Phosphoglycerate mutase 1
Gene Name Pgam1
Species Rattus norvegicus (Rat)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Interconversion of 3-and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity.
GO - Molecular function
  • 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity : IBA:GO_Central
  • bisphosphoglycerate mutase activity : IEA:UniProtKB-EC
  • hydrolase activity : IEA:UniProtKB-KW
  • phosphoglycerate mutase activity : IDA:RGD
  • protein kinase binding : IEA:Ensembl
GO - Biological process
  • gluconeogenesis : IBA:GO_Central
  • glycolytic process : IBA:GO_Central
  • regulation of glycolytic process : IEA:Ensembl
  • regulation of pentose-phosphate shunt : IBA:GO_Central
  • respiratory burst : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.