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P24369

Peptidyl-prolyl cis-trans isomerase B (P24369)

Uniprot ID P24369
Protein Name Peptidyl-prolyl cis-trans isomerase B
Gene Name Ppib
Species Mus musculus (Mouse)
Basic Information Experiments (3) Disease (1) Interactions
Signal peptide(a) Y Secretome P(b) 0.83
Function PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. .
GO - Molecular function
  • cyclosporin A binding : ISS:UniProtKB
  • peptidyl-prolyl cis-trans isomerase activity : ISS:UniProtKB
  • protein-containing complex binding : ISS:UniProtKB
  • RNA polymerase binding : ISO:MGI
GO - Biological process
  • bone development : ISO:MGI
  • chaperone-mediated protein folding : ISS:UniProtKB
  • positive regulation by host of viral genome replication : ISO:MGI
  • positive regulation by host of viral process : ISO:MGI
  • positive regulation of multicellular organism growth : ISO:MGI
  • protein peptidyl-prolyl isomerization : ISS:UniProtKB
  • protein stabilization : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.