Catalase (P24270)

Uniprot ID P24270
Protein Name Catalase
Gene Name Cat
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.471
Function Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.
GO - Molecular function
  • aminoacylase activity : IMP:MGI
  • antioxidant activity : ISO:MGI
  • catalase activity : IDA:MGI
  • enzyme binding : ISO:MGI
  • heme binding : ISO:MGI
  • metal ion binding : IEA:UniProtKB-KW
  • NADP binding : ISO:MGI
  • oxidoreductase activity, acting on peroxide as acceptor : IDA:MGI
  • protein homodimerization activity : ISO:MGI
  • signaling receptor binding : ISO:MGI
GO - Biological process
  • aerobic respiration : IMP:MGI
  • aging : IEA:Ensembl
  • cellular response to growth factor stimulus : IEA:Ensembl
  • cholesterol metabolic process : IMP:MGI
  • hemoglobin metabolic process : IMP:MGI
  • hydrogen peroxide catabolic process : IDA:MGI
  • kidney development : ISO:MGI
  • negative regulation of apoptotic process : ISO:MGI
  • negative regulation of NF-kappaB transcription factor activity : IDA:MGI
  • positive regulation of cell division : IEA:UniProtKB-KW
  • positive regulation of NF-kappaB transcription factor activity : IDA:MGI
  • positive regulation of phosphatidylinositol 3-kinase signaling : IDA:MGI
  • protein homotetramerization : ISO:MGI
  • protein tetramerization : ISO:MGI
  • response to activity : IEA:Ensembl
  • response to cadmium ion : IEA:Ensembl
  • response to estradiol : IEA:Ensembl
  • response to ethanol : IEA:Ensembl
  • response to fatty acid : IEA:Ensembl
  • response to hydrogen peroxide : IBA:GO_Central
  • response to hyperoxia : IEA:Ensembl
  • response to hypoxia : ISO:MGI
  • response to inactivity : IEA:Ensembl
  • response to insulin : IEA:Ensembl
  • response to L-ascorbic acid : IEA:Ensembl
  • response to lead ion : IEA:Ensembl
  • response to light intensity : IEA:Ensembl
  • response to oxidative stress : IDA:MGI
  • response to ozone : IEA:Ensembl
  • response to phenylpropanoid : IEA:Ensembl
  • response to reactive oxygen species : ISO:MGI
  • response to vitamin A : IEA:Ensembl
  • response to vitamin E : IEA:Ensembl
  • triglyceride metabolic process : IMP:MGI
  • ureteric bud development : ISO:MGI
  • UV protection : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.