Signal peptide(a) |
N |
Secretome P(b) |
|
Function |
May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. |
GO - Molecular function |
- amyloid-beta binding : ISO:RGD
- cytoskeletal protein binding : IDA:RGD
- identical protein binding : ISO:RGD
- metal ion binding : IEA:UniProtKB-KW
- microtubule binding : IDA:RGD
- protein homodimerization activity : ISS:UniProtKB
- protein-containing complex binding : ISO:RGD
- structural constituent of eye lens : TAS:RGD
- unfolded protein binding : ISO:RGD
|
GO - Biological process |
- aging : IEP:RGD
- apoptotic process involved in morphogenesis : ISO:RGD
- camera-type eye development : ISO:RGD
- cellular response to gamma radiation : ISO:RGD
- lens development in camera-type eye : ISO:RGD
- microtubule polymerization or depolymerization : IMP:RGD
- multicellular organism aging : IEP:RGD
- muscle organ development : ISO:RGD
- negative regulation of amyloid fibril formation : ISO:RGD
- negative regulation of apoptotic process : IDA:RGD
- negative regulation of cell growth : IDA:RGD
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process : ISO:RGD
- negative regulation of gene expression : ISO:RGD
- negative regulation of intracellular transport : ISO:RGD
- negative regulation of protein-containing complex assembly : ISO:RGD
- negative regulation of reactive oxygen species metabolic process : IDA:RGD
- negative regulation of transcription, DNA-templated : ISS:UniProtKB
- protein folding : IDA:RGD
- protein homooligomerization : ISO:RGD
- protein stabilization : ISO:RGD
- regulation of cell death : ISO:RGD
- response to estradiol : IEP:RGD
- response to hydrogen peroxide : IEP:RGD
- response to hypoxia : ISO:RGD
- stress-activated MAPK cascade : IMP:RGD
- tubulin complex assembly : ISO:RGD
|