| Signal peptide(a) |
Y |
Secretome P(b) |
0.928 |
| Function |
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. |
| GO - Molecular function |
- amyloid-beta binding : ISO:MGI
- cysteine-type endopeptidase inhibitor activity : ISO:MGI
- endopeptidase inhibitor activity : ISO:MGI
- identical protein binding : ISO:MGI
- peptidase inhibitor activity : ISO:MGI
- protease binding : ISO:MGI
|
| GO - Biological process |
- apoptotic process : IEA:Ensembl
- brain development : IEA:Ensembl
- cell activation : IEA:Ensembl
- cellular response to hydrogen peroxide : IEA:Ensembl
- circadian sleep/wake cycle, REM sleep : IEA:Ensembl
- defense response : ISO:MGI
- embryo implantation : IEA:Ensembl
- eye development : IEA:Ensembl
- negative regulation of blood vessel remodeling : IEA:Ensembl
- negative regulation of cell death : ISO:MGI
- negative regulation of collagen catabolic process : IEA:Ensembl
- negative regulation of cysteine-type endopeptidase activity : IBA:GO_Central
- negative regulation of elastin catabolic process : ISO:MGI
- negative regulation of extracellular matrix disassembly : IEA:Ensembl
- negative regulation of peptidase activity : ISO:MGI
- negative regulation of proteolysis : ISO:MGI
- positive regulation of cell proliferation : ISO:MGI
- positive regulation of DNA replication : ISO:MGI
- regulation of programmed cell death : ISO:MGI
- response to axon injury : IEA:Ensembl
- response to carbohydrate : IEA:Ensembl
- response to estradiol : IEA:Ensembl
- response to hypoxia : IEA:Ensembl
- response to nutrient levels : IEA:Ensembl
- response to oxidative stress : ISO:MGI
- salivary gland development : IEA:Ensembl
- Sertoli cell development : IEA:Ensembl
- supramolecular fiber organization : ISO:MGI
|