Signal peptide(a) |
Y |
Secretome P(b) |
0.0 |
Function |
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
GO - Molecular function |
- cytokine receptor activity : IBA:GO_Central
- phospholipid binding : ISO:MGI
- protease binding : ISO:MGI
|
GO - Biological process |
- activation of cysteine-type endopeptidase activity involved in apoptotic process : ISO:MGI
- activation of plasma proteins involved in acute inflammatory response : ISO:MGI
- blood coagulation : ISO:MGI
- cytokine-mediated signaling pathway : IBA:GO_Central
- positive regulation of angiogenesis : ISO:MGI
- positive regulation of endothelial cell proliferation : ISO:MGI
- positive regulation of platelet-derived growth factor receptor signaling pathway : ISO:MGI
- positive regulation of protein kinase B signaling : ISO:MGI
- positive regulation of smooth muscle cell migration : ISO:MGI
- protein processing : ISO:MGI
|