Annexin A7 (P20073)

Uniprot ID P20073
Protein Name Annexin A7
Gene Name ANXA7
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.85
Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • calcium-dependent phospholipid binding : IEA:UniProtKB-KW
  • calcium-dependent protein binding : IPI:UniProtKB
  • integrin binding : IPI:UniProtKB
  • RNA binding : HDA:UniProtKB
GO - Biological process
  • autophagy : IMP:UniProtKB
  • cell proliferation : IEA:Ensembl
  • cellular calcium ion homeostasis : IEA:Ensembl
  • cellular water homeostasis : IEA:Ensembl
  • epithelial cell differentiation : IEP:UniProtKB
  • hemostasis : IEA:Ensembl
  • membrane fusion : IEA:Ensembl
  • negative regulation of gene expression : IMP:UniProtKB
  • regulation of cell shape : IEA:Ensembl
  • response to calcium ion : IEA:Ensembl
  • response to organic cyclic compound : IEA:Ensembl
  • response to salt stress : IEA:Ensembl
  • social behavior : IEP:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.