| Signal peptide(a) |
Y |
Secretome P(b) |
0.0 |
| Function |
Involved in embryogenesis and cell differentiation. |
| GO - Molecular function |
- cytokine activity : IBA:GO_Central
- growth factor activity : IEA:UniProtKB-KW
- identical protein binding : ISS:AgBase
- protein heterodimerization activity : ISO:MGI
- transforming growth factor beta binding : ISS:AgBase
- type I transforming growth factor beta receptor binding : ISS:AgBase
- type II transforming growth factor beta receptor binding : ISS:AgBase
- type III transforming growth factor beta receptor binding : ISS:AgBase
|
| GO - Biological process |
- activation of MAPK activity : ISO:MGI
- animal organ morphogenesis : IMP:MGI
- BMP signaling pathway : IBA:GO_Central
- cell development : IBA:GO_Central
- cell-cell junction organization : ISS:AgBase
- cellular response to growth factor stimulus : IDA:MGI
- detection of hypoxia : ISS:AgBase
- embryonic neurocranium morphogenesis : ISO:MGI
- face morphogenesis : IEP:UniProtKB
- in utero embryonic development : IMP:MGI
- lung alveolus development : IMP:BHF-UCL
- mammary gland development : IDA:MGI
- negative regulation of cell proliferation : IDA:MGI
- negative regulation of macrophage cytokine production : ISS:AgBase
- negative regulation of neuron apoptotic process : IMP:MGI
- negative regulation of transforming growth factor beta receptor signaling pathway : ISO:MGI
- negative regulation of vascular smooth muscle cell proliferation : ISO:MGI
- ossification involved in bone remodeling : ISS:AgBase
- positive regulation of apoptotic process : IMP:MGI
- positive regulation of bone mineralization : ISS:AgBase
- positive regulation of cell division : IEA:UniProtKB-KW
- positive regulation of cell proliferation : ISS:BHF-UCL
- positive regulation of collagen biosynthetic process : ISS:AgBase
- positive regulation of epithelial to mesenchymal transition : IMP:BHF-UCL
- positive regulation of filopodium assembly : IMP:MGI
- positive regulation of gene expression : IDA:UniProtKB
- positive regulation of occluding junction disassembly : ISO:MGI
- positive regulation of pathway-restricted SMAD protein phosphorylation : IMP:BHF-UCL
- positive regulation of protein secretion : ISO:MGI
- positive regulation of SMAD protein signal transduction : IMP:BHF-UCL
- positive regulation of stress fiber assembly : ISO:MGI
- positive regulation of transcription by RNA polymerase II : IGI:MGI
- positive regulation of transcription, DNA-templated : IMP:BHF-UCL
- regulation of MAPK cascade : IBA:GO_Central
- response to estrogen : ISO:MGI
- response to hypoxia : ISS:AgBase
- response to progesterone : ISS:AgBase
- salivary gland morphogenesis : ISS:AgBase
- secondary palate development : IMP:BHF-UCL
- SMAD protein signal transduction : IBA:GO_Central
- transforming growth factor beta receptor signaling pathway : ISS:AgBase
|