| Signal peptide(a) |
N |
Secretome P(b) |
0.704 |
| Function |
Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity). . |
| GO - Molecular function |
- DNA-binding transcription factor activity : NAS:ProtInc
- DNA-binding transcription factor activity, RNA polymerase II-specific : ISM:NTNU_SB
- DNA-binding transcription repressor activity, RNA polymerase II-specific : IEA:Ensembl
- double-stranded DNA binding : TAS:ProtInc
- mRNA 3'-UTR binding : ISS:BHF-UCL
- polysome binding : IEA:Ensembl
- Rho GTPase binding : ISS:BHF-UCL
- RNA binding : HDA:UniProtKB
- RNA polymerase II regulatory region sequence-specific DNA binding : IEA:Ensembl
- transcription corepressor activity : TAS:ProtInc
|
| GO - Biological process |
- 3'-UTR-mediated mRNA stabilization : IC:BHF-UCL
- cellular hyperosmotic response : IMP:BHF-UCL
- cellular response to tumor necrosis factor : IMP:BHF-UCL
- fertilization : IEA:Ensembl
- in utero embryonic development : IEA:Ensembl
- male gonad development : IEA:Ensembl
- negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress : IMP:BHF-UCL
- negative regulation of necroptotic process : IMP:BHF-UCL
- negative regulation of skeletal muscle tissue development : IEA:Ensembl
- negative regulation of transcription by RNA polymerase II : TAS:ProtInc
- positive regulation of cytoplasmic translation : ISS:BHF-UCL
- positive regulation of organ growth : IEA:Ensembl
- response to cold : TAS:ProtInc
- spermatogenesis : IEA:Ensembl
|